Publications
SELECT: 2026 | 2025 – 2021 | 2020 – 2015
2026
Large-Scale Mutagenesis Identifies Sequence Changes That Bias Tau Toward CTE-like Aggregation
Dashnaw CM, Rastogi S, Morgan N, Memon I, Jaczynska K, Nguyen BA, Saelices L, White III CL, Shahmoradian S, Joachimiak LA
bioRxiv
Reply to: Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy
Kelly C, Nguyen BA, Singh V, Singh P, Bassett P, Schreiber S, Escobar CL, Kluve-Beckerman B, Evers B, Saelices L
bioRxiv
Cryo-EM reveals untwisted and non-periodic twist fibrils in ex vivo type B ATTRv-V30M fibrils
Afrin S, Fernandez-Ramirez MDC, Nguyen BA, Schreiber S, Kluve-Beckerman B, Saelices L
Amyloid
An N-terminal ATTR Fibril Segment Promotes Transthyretin Amyloid Nucleation and Polymorphism
Gadhe L, Nguyen BA, Fernandez-Ramirez MDC, Konstantoulea K, Lozen M, Tagad HD, Mendoza-Oliva A, Vaquer-Alicea J, Diamond MI, Saelices L, Louros NN
bioRxiv
Polymorphic IGLV6-57 AL amyloid fibrils and features of a shared folding pathway
Bassett PT, Nguyen BA, Singh V, Garrett PT, Moresco JJ, Eddy J, Afrin S, Pękała M, Lopez C, Evers BM, Ahmed Y, Grodin JL, Roth LR, Kaur G, Chung S, Morgan GJ, Yates JR, Saelices L
Nature Communications
Transthyretin amyloid fibrils adopt distinct folds in the brain
Afrin S, Nguyen BA, Bassett P, Fernandez-Ramirez MDC, Pedretti R, Villalon L, Kelly C, Lopez C, Madabushi M, Zhou A, Reis I, Taipa R, Evers B, Saelices L
bioRxiv
Cysteines are critical determinants of spontaneous and seeded tau aggregation in cells
Jayan P, Rastogi S, Bommareddy V, Dashnaw CM, Vaquer-Alicea J, Nguyen BA, Saelices L, Shahmoradian S, White CL 3rd, Diamond MI, Joachimiak LA
Research Square
Cryo-EM reveals structural variability of apolipoprotein A-I amyloid fibrils across organs, mutations, and clinical presentations
Nguyen BA, Fernandez-Ramirez MDC, Bassett P, Singh V, Singh P, Pękała M, Villalon L, Ahmed Y, Lemoff A, Evers B, Lopez C, Kluve-Beckerman B, Saelices L
Nature Communications
Structural polymorphism of ex-vivo ALECT2 amyloid fibrils revealed by cryo-EM
Afrin S, Nguyen BA, Singh V, Singh P, Bassett P, Pekala M, Evers B, Lopez C, Ahmed Y, Li L, Kallem RR, Lemoff A, Argyropoulos C, Kluve-Beckerman B, Saelices L
Nature Communications
Amyloid fibril polymorphism in the heart and liver of a patient with polyneuropathic ATTRv-V122Δ amyloidosis
Ahmed Y, Nguyen BA, Kelly C, Afrin S, Singh V, Evers B, Shelton J, Lopez Escobar C, Singh P, Pedretti R, Wang L, Bassett P, Fernandez-Ramirez MDC, Pekala M, Lemoff A, Kluve-Beckerman B, Saelices L
Communications Biology
A Shared Amyloid Architecture in Cardiac Fibrils from Three Neuropathy-Associated ATTR Variants
Fernandez-Ramirez MDC, Afrin S, Nguyen BA, Singh V, Pekala M, Singh P, Ahmed Y, Pedretti R, Lemoff A, Kluve-Beckerman B, Chhapra F, Eisenberg D, Saelices L
Structure