Publications
SELECT: 2026 | 2025 – 2021 | 2020 – 2015
2020
The inhibition of cellular toxicity of amyloid-β by dissociated transthyretin
Cao Q, Anderson DH, Liang WY, Chou J, Saelices L
Journal of Biological Chemistry
2019
A pair of peptides inhibits seeding of the hormone transporter transthyretin into amyloid fibrils
Saelices L, Nguyen BA, Chung K, Wang Y, Ortega A, Lee JH, Coelho T, Bijzet J, Benson MD, Eisenberg DS
Journal of Biological Chemistry
2018
Assessment of the effects of transthyretin peptide inhibitors in Drosophila models of neuropathic ATTR
Saelices L, Pokrzywa M, Pawelek K, Eisenberg DS
Neurobiology of Disease
Amyloid seeding of transthyretin by ex vivo cardiac fibrils and its inhibition
Saelices L, Chung K, Lee JH, Cohn W, Whitelegge JP, Benson MD, Eisenberg DS
Proceedings of the National Academy of Sciences of the United States of America
Crystal structures of amyloidogenic segments of human transthyretin
Saelices L, Sievers SA, Sawaya MR, Eisenberg DS
Protein Science
Common fibrillar spines of amyloid-β and human islet amyloid polypeptide revealed by microelectron diffraction and structure-based inhibitors
Krotee P, Griner SL, Sawaya MR, Cascio D, Rodriguez JA, Shi D, Philipp S, Murray K, Saelices L, Lee J, Seidler P, Glabe CG, Jiang L, Gonen T, Eisenberg DS
Journal of Biological Chemistry
2015
Uncovering the Mechanism of Aggregation of Human Transthyretin
Saelices L, Johnson LM, Liang WY, Sawaya MR, Cascio D, Ruchala P, Whitelegge J, Jiang L, Riek R, Eisenberg DS
Journal of Biological Chemistry